Leucocytosis after Distemper-parvo Vaccine in dogs

The FDA has received 261 reports of leucocytosis in dogs after Distemper-parvo Vaccine. That is 4.0% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

261Reports
69%Marked serious
12%Recovered
29%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
43 18%
1–2 days
39 17%
3–7 days
42 18%
1–4 weeks
71 30%
Over a month
39 17%

How the animals did

Recovered
30 11%
Recovered with lasting effects
2 0.8%
Still unwell when reported
113 43%
Died
18 6.9%
Euthanised
58 22%
Not known
40 15%

Problems reported at the same time

Age of the animals

Under 1 year
96
1–3 years
49
4–7 years
68
8–11 years
30
12+ years
18

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Distemper-parvo Vaccine cause leucocytosis in dogs?
261 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Leucocytosis with similar medicines

All reported side effects of Distemper-parvo Vaccine in dogs · Medicines most reported with leucocytosis