Leucocytosis after Diazepam in dogs

The FDA has received 37 reports of leucocytosis in dogs after Diazepam. That is 5.4% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

37Reports
84%Marked serious
2.7%Recovered
54%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
10 31%
1–2 days
7 22%
3–7 days
6 19%
1–4 weeks
7 22%
Over a month
2 6.3%

How the animals did

Recovered
1 2.7%
Still unwell when reported
15 41%
Died
6 16%
Euthanised
14 38%
Not known
1 2.7%

Problems reported at the same time

Age of the animals

Under 1 year
6
1–3 years
6
4–7 years
7
8–11 years
13
12+ years
5

About this medicine

Type: medicine.

Questions owners ask

Can Diazepam cause leucocytosis in dogs?
37 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Leucocytosis with similar medicines

All reported side effects of Diazepam in dogs · Medicines most reported with leucocytosis