Cyphenothrin + Fipronil side effects in dogs
287 reports sent to the FDA between 2012 and 2021 involve Cyphenothrin + Fipronil in dogs. The most reported problems were itching, vomiting, restlessness or agitation. 41% were marked serious.
287Reports
41%Marked serious
0.0%Only medicine involved
45%Recovered
3.8%Died or euthanised
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About this medicine
Fipronil kills fleas and ticks (spot-on).
Most reported side effects
Share = percentage of this medicine's reports that mention the problem. One report can list several problems.
Reports that it didn't work
Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.
How soon problems started
Time from the first dose to the first sign, where both dates were reported (156 reports).
How the animals did
Breeds named most often
Popular breeds appear more often because there are more of them.
- Labrador Retriever 23 reports
- Golden Retriever 17 reports
- Shih Tzu 16 reports
- Bichon Frise 16 reports
- Chihuahua 13 reports
- German Shepherd Dog 7 reports
- Miniature Schnauzer 7 reports
- Australian Shepherd Dog 6 reports
- Yorkshire Terrier 6 reports
- Pug 6 reports
Other flea and tick treatments for dogs
Spinosad (Comfortis)57,095 reports · 7.7% seriousLufenuron + Milbemycin Oxime (Sentinel)26,051 reports · 24% seriousImidacloprid + Moxidectin (Advantage Multi)13,117 reports · 57% seriousNitenpyram (Capstar)10,782 reports · 10.0% seriousLufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum)9,966 reports · 40% seriousFipronil + S-methoprene (Frontline Plus)2,954 reports · 49% seriousFlumethrin + Imidacloprid (Seresto)2,273 reports · 25% seriousImidacloprid1,908 reports · 11% serious