Pyoderma after Cyclosporine (Atopica) in dogs

201 reports to the FDA describe pyoderma in dogs given Cyclosporine. That is 1.3% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

201Reports

15%Marked serious

3.5%Recovered

7.0%Died or euthanised

65 daysTypical onset

How soon it started

Same day

2 8.3%

1–2 days

0 0.0%

3–7 days

2 8.3%

1–4 weeks

6 25%

Over a month

14 58%

How the animals did

Recovered

7 3.5%

Still unwell when reported

25 12%

Died

11 5.5%

Euthanised

3 1.5%

Not known

155 77%

Problems reported at the same time

Itching

48 24%

Skin rash or irritation

48 24%

Didn't work as expected

43 21%

37 18%

31 15%

30 15%

20 10.0%

19 9.5%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause pyoderma in dogs?: 201 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 65 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pyoderma with similar medicines

Pyoderma after Oclacitinib (Apoquel) 218 reports · 0.8% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with pyoderma