Hind limb paresis after Cyclosporine (Atopica) in dogs

84 reports to the FDA describe hind limb paresis in dogs given Cyclosporine. That is 0.5% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

84Reports

32%Marked serious

3.6%Recovered

9.5%Died or euthanised

11 daysTypical onset

How soon it started

Same day

7 32%

1–2 days

1 4.5%

3–7 days

2 9.1%

1–4 weeks

7 32%

Over a month

5 23%

How the animals did

Recovered

3 3.6%

Still unwell when reported

15 18%

Died

3 3.6%

Euthanised

5 6.0%

Not known

58 69%

Problems reported at the same time

21 25%

20 24%

19 23%

17 20%

16 19%

14 17%

13 15%

11 13%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause hind limb paresis in dogs?: 84 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 11 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hind limb paresis with similar medicines

Hind limb paresis after Oclacitinib (Apoquel) 57 reports · 0.2% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with hind limb paresis