Leucocytosis after Cephalexin in dogs

The FDA has received 74 reports of leucocytosis in dogs after Cephalexin. That is 2.8% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

74Reports
73%Marked serious
14%Recovered
41%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
12 19%
1–2 days
7 11%
3–7 days
15 24%
1–4 weeks
10 16%
Over a month
19 30%

How the animals did

Recovered
8 11%
Recovered with lasting effects
2 2.7%
Still unwell when reported
27 36%
Died
10 14%
Euthanised
20 27%
Not known
7 9.5%

Problems reported at the same time

Age of the animals

Under 1 year
5
1–3 years
15
4–7 years
20
8–11 years
29
12+ years
5

About this medicine

Type: medicine.

Questions owners ask

Can Cephalexin cause leucocytosis in dogs?
74 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Leucocytosis with similar medicines

All reported side effects of Cephalexin in dogs · Medicines most reported with leucocytosis