Neutrophilia after Capromorelin (Entyce) in dogs

The FDA has received 72 reports of neutrophilia in dogs after Capromorelin. That is 4.8% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

72Reports

96%Marked serious

1.4%Recovered

47%Died or euthanised

8 daysTypical onset

How soon it started

Same day

11 17%

1–2 days

12 18%

3–7 days

8 12%

1–4 weeks

15 23%

Over a month

19 29%

How the animals did

Recovered

1 1.4%

Still unwell when reported

23 32%

Died

13 18%

Euthanised

21 29%

Not known

14 19%

Problems reported at the same time

60 83%

46 64%

42 58%

40 56%

39 54%

35 49%

34 47%

32 44%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Capromorelin stimulates appetite.

Products with this ingredient include Entyce, Elura. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Capromorelin cause neutrophilia in dogs?: 72 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 8 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neutrophilia with similar medicines

Neutrophilia after Maropitant (Cerenia) 567 reports · 4.8% of its reports
Neutrophilia after Mirtazapine (Mirataz) 35 reports · 12% of its reports

All reported side effects of Capromorelin in dogs · Medicines most reported with neutrophilia