Malaise after Capromorelin (Entyce) in dogs

The FDA has received 25 reports of malaise in dogs after Capromorelin. That is 1.7% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

25Reports

52%Marked serious

16%Recovered

16%Died or euthanised

21 daysTypical onset

How soon it started

Same day

5 23%

1–2 days

1 4.5%

3–7 days

2 9.1%

1–4 weeks

4 18%

Over a month

10 45%

How the animals did

Recovered

4 16%

Still unwell when reported

10 40%

Died

3 12%

Euthanised

1 4.0%

Not known

7 28%

Problems reported at the same time

13 52%

10 40%

9 36%

6 24%

4 16%

Didn't work as expected

4 16%

Tremors

4 16%

Death

4 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Capromorelin stimulates appetite.

Products with this ingredient include Entyce, Elura. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Capromorelin cause malaise in dogs?: 25 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 21 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Malaise with similar medicines

Malaise after Maropitant (Cerenia) 121 reports · 1.0% of its reports

All reported side effects of Capromorelin in dogs · Medicines most reported with malaise