Malaise after Maropitant (Cerenia) in dogs

The FDA has received 121 reports of malaise in dogs after Maropitant. That is 1.0% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

121Reports

66%Marked serious

12%Recovered

29%Died or euthanised

5 daysTypical onset

How soon it started

Same day

29 28%

1–2 days

15 14%

3–7 days

16 15%

1–4 weeks

18 17%

Over a month

27 26%

How the animals did

Recovered

14 12%

Still unwell when reported

55 45%

Died

20 17%

Euthanised

15 12%

Not known

17 14%

Problems reported at the same time

79 65%

66 55%

64 53%

35 29%

35 29%

34 28%

28 23%

21 17%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause malaise in dogs?: 121 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Malaise with similar medicines

Malaise after Capromorelin (Entyce) 25 reports · 1.7% of its reports

All reported side effects of Maropitant in dogs · Medicines most reported with malaise