Swelling after Bupivacaine Lipsome in dogs

The FDA has received 29 reports of swelling in dogs after Bupivacaine Lipsome. That is 32% of all reports for this medicine, compared with 2.8% across reports for all dog medicines, so it is reported unusually often with this medicine.

29Reports
79%Marked serious
41%Recovered
6.9%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
10 40%
1–2 days
6 24%
3–7 days
3 12%
1–4 weeks
4 16%
Over a month
2 8.0%

How the animals did

Recovered
12 41%
Died
1 3.4%
Euthanised
1 3.4%
Not known
15 52%

Problems reported at the same time

Loss of appetite
5 17%
Skin redness
5 17%
Discomfort
4 14%
Fever
3 10%
Surgical site disorder
3 10%
Lameness
3 10%

Age of the animals

Under 1 year
1
1–3 years
7
4–7 years
5
8–11 years
9
12+ years
0

About this medicine

Type: medicine.

Questions owners ask

Can Bupivacaine Lipsome cause swelling in dogs?
29 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Swelling with similar medicines

All reported side effects of Bupivacaine Lipsome in dogs · Medicines most reported with swelling