Lethargy after Betamethasone + Gentamicin in dogs

The FDA has received 54 reports of lethargy in dogs after Betamethasone + Gentamicin. That is 18% of all reports for this medicine, compared with 11% across reports for all dog medicines, so it is reported unusually often with this medicine.

54Reports
57%Marked serious
24%Recovered
20%Died or euthanised
31 daysTypical onset
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How soon it started

Same day
11 26%
1–2 days
2 4.8%
3–7 days
5 12%
1–4 weeks
3 7.1%
Over a month
21 50%

How the animals did

Recovered
10 19%
Recovered with lasting effects
3 5.6%
Still unwell when reported
12 22%
Died
3 5.6%
Euthanised
8 15%
Not known
18 33%

Problems reported at the same time

21 39%
16 30%
11 20%
11 20%
Behaviour change
8 15%

Age of the animals

Under 1 year
4
1–3 years
16
4–7 years
14
8–11 years
16
12+ years
3

About this medicine

Type: medicine.

Questions owners ask

Can Betamethasone + Gentamicin cause lethargy in dogs?
54 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 31 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Betamethasone + Gentamicin in dogs · Medicines most reported with lethargy