Leucocytosis after Betamethasone + Florfenicol + Terbinafine in dogs

The FDA has received 29 reports of leucocytosis in dogs after Betamethasone + Florfenicol + Terbinafine. That is 1.2% of all reports for this medicine, compared with 1.0% across reports for all dog medicines.

29Reports
93%Marked serious
17%Recovered
21%Died or euthanised
10 daysTypical onset
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How soon it started

Same day
1 4.8%
1–2 days
3 14%
3–7 days
4 19%
1–4 weeks
10 48%
Over a month
3 14%

How the animals did

Recovered
4 14%
Recovered with lasting effects
1 3.4%
Still unwell when reported
8 28%
Died
2 6.9%
Euthanised
4 14%
Not known
10 34%

Problems reported at the same time

16 55%
14 48%
11 38%
10 34%
Monocytosis
9 31%

Age of the animals

Under 1 year
2
1–3 years
8
4–7 years
6
8–11 years
7
12+ years
6

About this medicine

Type: medicine.

Questions owners ask

Can Betamethasone + Florfenicol + Terbinafine cause leucocytosis in dogs?
29 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 10 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Leucocytosis with similar medicines

All reported side effects of Betamethasone + Florfenicol + Terbinafine in dogs · Medicines most reported with leucocytosis