Pyuria after Bedinvetmab (Librela) in dogs

138 reports to the FDA describe pyuria in dogs given Bedinvetmab. That is 0.7% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

138Reports
83%Marked serious
2.9%Recovered
17%Died or euthanised
24 daysTypical onset
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How soon it started

Same day
9 7.8%
1–2 days
14 12%
3–7 days
10 8.7%
1–4 weeks
32 28%
Over a month
50 43%

How the animals did

Recovered
3 2.2%
Recovered with lasting effects
1 0.7%
Still unwell when reported
98 71%
Died
4 2.9%
Euthanised
19 14%
Not known
13 9.4%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
2
4–7 years
9
8–11 years
49
12+ years
77

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause pyuria in dogs?
138 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 24 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Bedinvetmab in dogs · Medicines most reported with pyuria