Neutrophilia after Bedinvetmab (Librela) in dogs

314 reports to the FDA describe neutrophilia in dogs given Bedinvetmab. That is 1.6% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

314Reports
87%Marked serious
2.9%Recovered
41%Died or euthanised
8 daysTypical onset
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How soon it started

Same day
34 13%
1–2 days
49 19%
3–7 days
43 16%
1–4 weeks
64 25%
Over a month
71 27%

How the animals did

Recovered
9 2.9%
Still unwell when reported
161 51%
Died
37 12%
Euthanised
92 29%
Not known
15 4.8%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
5
4–7 years
31
8–11 years
113
12+ years
162

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause neutrophilia in dogs?
314 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 8 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neutrophilia with similar medicines

All reported side effects of Bedinvetmab in dogs · Medicines most reported with neutrophilia