Intervertebral disc disease after Bedinvetmab (Librela) in dogs

123 reports to the FDA describe intervertebral disc disease in dogs given Bedinvetmab. That is 0.6% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

123Reports

86%Marked serious

5.7%Recovered

28%Died or euthanised

18 daysTypical onset

How soon it started

Same day

17 15%

1–2 days

15 13%

3–7 days

10 8.9%

1–4 weeks

34 30%

Over a month

36 32%

How the animals did

Recovered

7 5.7%

Still unwell when reported

69 56%

Died

6 4.9%

Euthanised

29 24%

Not known

12 9.8%

Problems reported at the same time

Weakness

37 30%

Wobbliness (ataxia)

36 29%

Death

34 28%

Proprioception deficit

28 23%

Loss of appetite

26 21%

Abnormal radiograph finding

22 18%

Liver problems

20 16%

Lethargy

17 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause intervertebral disc disease in dogs?: 123 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 18 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Bedinvetmab in dogs · Medicines most reported with intervertebral disc disease