Proprioception deficit after Bedinvetmab (Librela) in dogs

The FDA has received 814 reports of proprioception deficit in dogs after Bedinvetmab. That is 4.1% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

814Reports

78%Marked serious

5.8%Recovered

24%Died or euthanised

10 daysTypical onset

How soon it started

Same day

120 17%

1–2 days

110 16%

3–7 days

105 15%

1–4 weeks

162 23%

Over a month

211 30%

How the animals did

Recovered

47 5.8%

Still unwell when reported

524 64%

Died

36 4.4%

Euthanised

157 19%

Not known

50 6.1%

Problems reported at the same time

336 41%

292 36%

191 23%

136 17%

115 14%

112 14%

92 11%

Musculoskeletal disorder

91 11%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

292

12+ years

461

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause proprioception deficit in dogs?: 814 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 10 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Proprioception deficit with similar medicines

Proprioception deficit after Lokivetmab (Cytopoint) 38 reports · 0.6% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with proprioception deficit