Abnormal radiograph finding after Bedinvetmab (Librela) in dogs

The FDA has received 659 reports of abnormal radiograph finding in dogs after Bedinvetmab. That is 3.4% of all reports for this medicine, compared with 0.9% across reports for all dog medicines, so it is reported unusually often with this medicine.

659Reports
85%Marked serious
2.0%Recovered
28%Died or euthanised
25 daysTypical onset
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How soon it started

Same day
66 13%
1–2 days
61 12%
3–7 days
53 10%
1–4 weeks
117 22%
Over a month
225 43%

How the animals did

Recovered
12 1.8%
Recovered with lasting effects
1 0.2%
Still unwell when reported
422 64%
Died
36 5.5%
Euthanised
146 22%
Not known
42 6.4%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
7
4–7 years
96
8–11 years
317
12+ years
237

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause abnormal radiograph finding in dogs?
659 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 25 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal radiograph finding with similar medicines

All reported side effects of Bedinvetmab in dogs · Medicines most reported with abnormal radiograph finding