Bone and joint disorder after Bedinvetmab (Librela) in dogs

379 reports to the FDA describe bone and joint disorder in dogs given Bedinvetmab. That is 1.9% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

379Reports
67%Marked serious
1.8%Recovered
14%Died or euthanised
34 daysTypical onset
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How soon it started

Same day
33 13%
1–2 days
21 8.1%
3–7 days
16 6.2%
1–4 weeks
51 20%
Over a month
139 53%

How the animals did

Recovered
5 1.3%
Recovered with lasting effects
2 0.5%
Still unwell when reported
264 70%
Died
10 2.6%
Euthanised
44 12%
Not known
54 14%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
8
4–7 years
76
8–11 years
200
12+ years
74

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause bone and joint disorder in dogs?
379 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 34 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Bone and joint disorder with similar medicines

All reported side effects of Bedinvetmab in dogs · Medicines most reported with bone and joint disorder