Hyposthenuria after Bedinvetmab (Librela) in dogs

The FDA has received 206 reports of hyposthenuria in dogs after Bedinvetmab. That is 1.1% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

206Reports

50%Marked serious

4.4%Recovered

6.8%Died or euthanised

14 daysTypical onset

How soon it started

Same day

20 11%

1–2 days

31 17%

3–7 days

27 15%

1–4 weeks

53 28%

Over a month

55 30%

How the animals did

Recovered

9 4.4%

Still unwell when reported

175 85%

Died

5 2.4%

Euthanised

9 4.4%

Not known

8 3.9%

Problems reported at the same time

139 67%

138 67%

54 26%

51 25%

48 23%

31 15%

30 15%

Inappropriate urination

30 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

111

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause hyposthenuria in dogs?: 206 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 14 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyposthenuria with similar medicines

Hyposthenuria after Lokivetmab (Cytopoint) 26 reports · 0.4% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with hyposthenuria