Hyponatremia after Bedinvetmab (Librela) in dogs

36 reports to the FDA describe hyponatremia in dogs given Bedinvetmab. That is 0.2% of all reports for this medicine, compared with 0.2% across reports for all dog medicines.

36Reports

89%Marked serious

2.8%Recovered

56%Died or euthanised

18 daysTypical onset

How soon it started

Same day

0 0.0%

1–2 days

6 21%

3–7 days

2 6.9%

1–4 weeks

9 31%

Over a month

12 41%

How the animals did

Recovered

1 2.8%

Still unwell when reported

11 31%

Died

4 11%

Euthanised

16 44%

Not known

4 11%

Problems reported at the same time

21 58%

20 56%

20 56%

19 53%

18 50%

17 47%

14 39%

14 39%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause hyponatremia in dogs?: 36 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 18 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyponatremia with similar medicines

Hyponatremia after Lokivetmab (Cytopoint) 33 reports · 0.5% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with hyponatremia