Anxiety after Bedinvetmab (Librela) in dogs

The FDA has received 329 reports of anxiety in dogs after Bedinvetmab. That is 1.7% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

329Reports

61%Marked serious

12%Recovered

22%Died or euthanised

7 daysTypical onset

How soon it started

Same day

76 27%

1–2 days

35 12%

3–7 days

33 12%

1–4 weeks

71 25%

Over a month

67 24%

How the animals did

Recovered

37 11%

Recovered with lasting effects

3 0.9%

Still unwell when reported

156 47%

Died

13 4.0%

Euthanised

61 19%

Not known

59 18%

Problems reported at the same time

118 36%

74 22%

71 22%

66 20%

63 19%

55 17%

Restlessness or agitation

52 16%

Weakness

52 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

104

12+ years

179

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause anxiety in dogs?: 329 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Anxiety with similar medicines

Anxiety after Lokivetmab (Cytopoint) 79 reports · 1.2% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with anxiety