Behaviour change after Bedinvetmab (Librela) in dogs

673 reports to the FDA describe behaviour change in dogs given Bedinvetmab. That is 3.4% of all reports for this medicine, compared with 2.5% across reports for all dog medicines.

673Reports

61%Marked serious

12%Recovered

25%Died or euthanised

5 daysTypical onset

How soon it started

Same day

149 25%

1–2 days

112 19%

3–7 days

78 13%

1–4 weeks

106 18%

Over a month

143 24%

How the animals did

Recovered

76 11%

Recovered with lasting effects

4 0.6%

Still unwell when reported

300 45%

Died

44 6.5%

Euthanised

127 19%

Not known

122 18%

Problems reported at the same time

182 27%

170 25%

137 20%

124 18%

106 16%

99 15%

93 14%

92 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

225

12+ years

344

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause behaviour change in dogs?: 673 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Behaviour change with similar medicines

Behaviour change after Lokivetmab (Cytopoint) 289 reports · 4.4% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with behaviour change