Restlessness or agitation after Bedinvetmab (Librela) in dogs

The FDA has received 416 reports of restlessness or agitation in dogs after Bedinvetmab. That is 2.1% of all reports for this medicine, compared with 1.6% across reports for all dog medicines.

416Reports

62%Marked serious

19%Recovered

24%Died or euthanised

2 daysTypical onset

How soon it started

Same day

108 30%

1–2 days

79 22%

3–7 days

44 12%

1–4 weeks

61 17%

Over a month

73 20%

How the animals did

Recovered

77 19%

Recovered with lasting effects

1 0.2%

Still unwell when reported

188 45%

Died

25 6.0%

Euthanised

75 18%

Not known

50 12%

Problems reported at the same time

160 38%

114 27%

100 24%

77 19%

73 18%

63 15%

60 14%

58 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

122

12+ years

242

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause restlessness or agitation in dogs?: 416 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Restlessness or agitation with similar medicines

Restlessness or agitation after Lokivetmab (Cytopoint) 144 reports · 2.2% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with restlessness or agitation