Abnormal histology after Bedinvetmab (Librela) in dogs

26 reports to the FDA describe abnormal histology in dogs given Bedinvetmab. That is 0.1% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

26Reports
92%Marked serious
7.7%Recovered
27%Died or euthanised
59 daysTypical onset
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How soon it started

Same day
1 5.9%
1–2 days
0 0.0%
3–7 days
1 5.9%
1–4 weeks
4 24%
Over a month
11 65%

How the animals did

Recovered
2 7.7%
Still unwell when reported
17 65%
Euthanised
7 27%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
2
4–7 years
4
8–11 years
12
12+ years
8

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause abnormal histology in dogs?
26 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 59 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Bedinvetmab in dogs · Medicines most reported with abnormal histology