Neutropenia after Ampicillin in dogs

57 reports to the FDA describe neutropenia in dogs given Ampicillin. That is 5.8% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

57Reports
95%Marked serious
8.8%Recovered
58%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
6 13%
1–2 days
11 23%
3–7 days
7 15%
1–4 weeks
5 11%
Over a month
18 38%

How the animals did

Recovered
5 8.8%
Still unwell when reported
16 28%
Died
10 18%
Euthanised
23 40%
Not known
3 5.3%

Problems reported at the same time

Age of the animals

Under 1 year
10
1–3 years
11
4–7 years
11
8–11 years
14
12+ years
9

About this medicine

Type: medicine.

Questions owners ask

Can Ampicillin cause neutropenia in dogs?
57 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neutropenia with similar medicines

All reported side effects of Ampicillin in dogs · Medicines most reported with neutropenia