Neutropenia after Cephalexin in dogs

The FDA has received 32 reports of neutropenia in dogs after Cephalexin. That is 1.2% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

32Reports
72%Marked serious
19%Recovered
34%Died or euthanised
31 daysTypical onset
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How soon it started

Same day
0 0.0%
1–2 days
3 14%
3–7 days
1 4.8%
1–4 weeks
6 29%
Over a month
11 52%

How the animals did

Recovered
5 16%
Recovered with lasting effects
1 3.1%
Still unwell when reported
10 31%
Died
8 25%
Euthanised
3 9.4%
Not known
5 16%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
11
4–7 years
14
8–11 years
5
12+ years
2

About this medicine

Type: medicine.

Questions owners ask

Can Cephalexin cause neutropenia in dogs?
32 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 31 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neutropenia with similar medicines

All reported side effects of Cephalexin in dogs · Medicines most reported with neutropenia