Drooling after Amoxicillin + Clavulanate (Clavamox) in dogs

The FDA has received 130 reports of drooling in dogs after Amoxicillin + Clavulanate. That is 2.4% of all reports for this medicine, compared with 1.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

130Reports
61%Marked serious
15%Recovered
37%Died or euthanised
8 daysTypical onset
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How soon it started

Same day
19 20%
1–2 days
14 15%
3–7 days
14 15%
1–4 weeks
29 31%
Over a month
18 19%

How the animals did

Recovered
19 15%
Still unwell when reported
35 27%
Died
24 18%
Euthanised
24 18%
Not known
28 22%

Problems reported at the same time

Age of the animals

Under 1 year
29
1–3 years
27
4–7 years
22
8–11 years
29
12+ years
20

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause drooling in dogs?
130 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 8 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Drooling with similar medicines

All reported side effects of Amoxicillin + Clavulanate in dogs · Medicines most reported with drooling