Dermal mass after Amoxicillin + Clavulanate (Clavamox) in dogs

The FDA has received 22 reports of dermal mass in dogs after Amoxicillin + Clavulanate. That is 0.4% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

22Reports

73%Marked serious

0.0%Recovered

14%Died or euthanised

39 daysTypical onset

How soon it started

Same day

1 6.3%

1–2 days

0 0.0%

3–7 days

3 19%

1–4 weeks

3 19%

Over a month

9 56%

How the animals did

Still unwell when reported

15 68%

Died

1 4.5%

Euthanised

2 9.1%

Not known

4 18%

Problems reported at the same time

Didn't work as expected

10 45%

Vomiting

7 32%

Loss of appetite

6 27%

Skin rash or irritation

5 23%

4 18%

4 18%

3 14%

3 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause dermal mass in dogs?: 22 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 39 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Amoxicillin + Clavulanate in dogs · Medicines most reported with dermal mass