Crust after Amoxicillin + Clavulanate (Clavamox) in dogs

The FDA has received 66 reports of crust in dogs after Amoxicillin + Clavulanate. That is 1.2% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

66Reports
48%Marked serious
7.6%Recovered
14%Died or euthanised
21 daysTypical onset
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How soon it started

Same day
3 6.8%
1–2 days
3 6.8%
3–7 days
5 11%
1–4 weeks
17 39%
Over a month
16 36%

How the animals did

Recovered
2 3.0%
Recovered with lasting effects
3 4.5%
Still unwell when reported
29 44%
Died
5 7.6%
Euthanised
4 6.1%
Not known
23 35%

Problems reported at the same time

Age of the animals

Under 1 year
5
1–3 years
10
4–7 years
17
8–11 years
20
12+ years
12

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause crust in dogs?
66 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 21 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Crust with similar medicines

All reported side effects of Amoxicillin + Clavulanate in dogs · Medicines most reported with crust