Amitriptyline side effects in dogs

130 reports sent to the FDA between 2002 and 2026 involve Amitriptyline in dogs. The most reported problems were vomiting, lethargy, itching. 37% were marked serious.

130Reports
37%Marked serious
0.8%Only medicine involved
52%Recovered
6.9%Died or euthanised
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About this medicine

Type: medicine.

Most reported side effects

52 40%
26 20%
Itching
17 13%
Liver problems
15 12%
Loss of appetite
13 10%
Diarrhea
13 10%
Behaviour change
11 8.5%
Seizures
10 7.7%
Breathing problems
8 6.2%
Kidney problems
7 5.4%
Overdose
7 5.4%
Lameness
6 4.6%
Anxiety
6 4.6%
Skin redness
6 4.6%
Excessive thirst
6 4.6%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't work as expected
19 15%
Didn't stop fleas
1 0.8%
Didn't stop worms
1 0.8%
Didn't prevent heartworm
1 0.8%

How soon problems started

Same day
9 12%
1–2 days
2 2.6%
3–7 days
7 9.0%
1–4 weeks
8 10%
Over a month
52 67%

Time from the first dose to the first sign, where both dates were reported (78 reports).

How the animals did

Recovered
60 46%
Recovered with lasting effects
8 6.2%
Still unwell when reported
34 26%
Died
3 2.3%
Euthanised
6 4.6%
Not known
19 15%

Breeds named most often

Popular breeds appear more often because there are more of them.

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