Hypokalaemia after Velagliflozin (Senvelgo) in cats

235 reports to the FDA describe hypokalaemia in cats given Velagliflozin. That is 4.9% of all reports for this medicine, compared with 0.5% across reports for all cat medicines, so it is reported unusually often with this medicine.

235Reports

74%Marked serious

5.5%Recovered

32%Died or euthanised

8 daysTypical onset

How soon it started

Same day

13 6.3%

1–2 days

47 23%

3–7 days

42 20%

1–4 weeks

41 20%

Over a month

63 31%

How the animals did

Recovered

13 5.5%

Still unwell when reported

54 23%

Died

15 6.4%

Euthanised

60 26%

Not known

93 40%

Problems reported at the same time

160 68%

121 51%

112 48%

112 48%

102 43%

102 43%

93 40%

89 38%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Velagliflozin treats diabetes in cats (oral, an SGLT2 inhibitor).

Products with this ingredient include Senvelgo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Velagliflozin cause hypokalaemia in cats?: 235 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 8 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypokalaemia with similar medicines

Hypokalaemia after Bexagliflozin (Bexacat) 160 reports · 3.9% of its reports
Hypokalaemia after Insulin 57 reports · 1.5% of its reports
Hypokalaemia after Methimazole 31 reports · 1.7% of its reports

All reported side effects of Velagliflozin in cats · Medicines most reported with hypokalaemia