Kidney problems after Velagliflozin (Senvelgo) in cats

445 reports to the FDA describe kidney problems in cats given Velagliflozin. That is 9.3% of all reports for this medicine, compared with 4.5% across reports for all cat medicines, so it is reported unusually often with this medicine.

445Reports
44%Marked serious
3.6%Recovered
22%Died or euthanised
18 daysTypical onset
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How soon it started

Same day
25 6.5%
1–2 days
53 14%
3–7 days
69 18%
1–4 weeks
75 20%
Over a month
162 42%

How the animals did

Recovered
16 3.6%
Still unwell when reported
65 15%
Died
17 3.8%
Euthanised
80 18%
Not known
267 60%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
3
4–7 years
44
8–11 years
145
12+ years
240

About this medicine

Velagliflozin treats diabetes in cats (oral, an SGLT2 inhibitor).

Products with this ingredient include Senvelgo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Velagliflozin cause kidney problems in cats?
445 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 18 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

All reported side effects of Velagliflozin in cats · Medicines most reported with kidney problems