Application site reaction after Spinosad (Comfortis) in cats
The FDA has received 25 reports of application site reaction in cats after Spinosad. That is 0.2% of all reports for this medicine, compared with 8.1% across reports for all cat medicines, so it is reported less often than average with this medicine.
25Reports
24%Marked serious
32%Recovered
0.0%Died or euthanised
35 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Spinosad kills fleas; monthly chewable.
Products with this ingredient include Comfortis. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Spinosad cause application site reaction in cats?
- 25 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 35 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Application site reaction with similar medicines
- Application site reaction after Nitenpyram (Capstar) 41 reports · 0.5% of its reports
- Application site reaction after Imidacloprid + Moxidectin (Advantage Multi) 1,047 reports · 13% of its reports
- Application site reaction after Flumethrin + Imidacloprid (Seresto) 187 reports · 28% of its reports
- Application site reaction after Imidacloprid + Pyriproxyfen 45 reports · 6.9% of its reports
- Application site reaction after Fipronil + S-methoprene (Frontline Plus) 28 reports · 7.6% of its reports
All reported side effects of Spinosad in cats · Medicines most reported with application site reaction