Inappropriate urination after Sarolaner + Selamectin (Revolution Plus) in cats
The FDA has received 39 reports of inappropriate urination in cats after Sarolaner + Selamectin. That is 0.5% of all reports for this medicine, compared with 0.7% across reports for all cat medicines.
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Sarolaner kills fleas, ticks and some mites; monthly. Selamectin prevents heartworm and treats fleas, ear mites and some worms (spot-on).
Products with this combination include Revolution Plus. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.
Questions owners ask
- Can Sarolaner + Selamectin cause inappropriate urination in cats?
- 39 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 1 day of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Inappropriate urination with similar medicines
- Inappropriate urination after Fluralaner (Bravecto) 69 reports · 0.6% of its reports
All reported side effects of Sarolaner + Selamectin in cats · Medicines most reported with inappropriate urination