Inappropriate urination after Fluralaner (Bravecto) in cats

69 reports to the FDA describe inappropriate urination in cats given Fluralaner. That is 0.6% of all reports for this medicine, compared with 0.7% across reports for all cat medicines.

69Reports
84%Marked serious
14%Recovered
26%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
19 33%
1–2 days
14 24%
3–7 days
9 16%
1–4 weeks
9 16%
Over a month
7 12%

How the animals did

Recovered
10 14%
Still unwell when reported
31 45%
Died
7 10%
Euthanised
11 16%
Not known
10 14%

Problems reported at the same time

Age of the animals

Under 1 year
4
1–3 years
10
4–7 years
18
8–11 years
14
12+ years
23

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause inappropriate urination in cats?
69 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Inappropriate urination with similar medicines

All reported side effects of Fluralaner in cats · Medicines most reported with inappropriate urination