Death after Fluralaner (Bravecto) in cats

384 reports to the FDA describe death in cats given Fluralaner. That is 3.6% of all reports for this medicine, compared with 8.9% across reports for all cat medicines, so it is reported less often than average with this medicine.

384Reports
99%Marked serious
0.0%Recovered
99%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
62 21%
1–2 days
87 29%
3–7 days
41 14%
1–4 weeks
30 10%
Over a month
75 25%

How the animals did

Still unwell when reported
2 0.5%
Died
212 55%
Euthanised
169 44%
Not known
1 0.3%

Problems reported at the same time

Age of the animals

Under 1 year
37
1–3 years
92
4–7 years
71
8–11 years
72
12+ years
87

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause death in cats?
384 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Death with similar medicines

All reported side effects of Fluralaner in cats · Medicines most reported with death