Seizures after Fluralaner (Bravecto) in cats

The FDA has received 211 reports of seizures in cats after Fluralaner. That is 2.0% of all reports for this medicine, compared with 2.6% across reports for all cat medicines.

211Reports
100%Marked serious
28%Recovered
27%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
57 35%
1–2 days
38 24%
3–7 days
20 12%
1–4 weeks
26 16%
Over a month
20 12%

How the animals did

Recovered
58 27%
Recovered with lasting effects
2 0.9%
Still unwell when reported
68 32%
Died
30 14%
Euthanised
28 13%
Not known
25 12%

Problems reported at the same time

Age of the animals

Under 1 year
23
1–3 years
48
4–7 years
46
8–11 years
26
12+ years
57

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause seizures in cats?
211 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Seizures with similar medicines

All reported side effects of Fluralaner in cats · Medicines most reported with seizures