Loss of appetite after Fluralaner (Bravecto) in cats

The FDA has received 981 reports of loss of appetite in cats after Fluralaner. That is 9.2% of all reports for this medicine, compared with 14% across reports for all cat medicines.

981Reports
80%Marked serious
22%Recovered
12%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
302 37%
1–2 days
280 35%
3–7 days
92 11%
1–4 weeks
68 8.4%
Over a month
69 8.5%

How the animals did

Recovered
208 21%
Recovered with lasting effects
11 1.1%
Still unwell when reported
529 54%
Died
51 5.2%
Euthanised
67 6.8%
Not known
115 12%

Problems reported at the same time

595 61%
314 32%
127 13%
117 12%
112 11%

Age of the animals

Under 1 year
63
1–3 years
234
4–7 years
242
8–11 years
214
12+ years
206

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause loss of appetite in cats?
981 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of appetite with similar medicines

All reported side effects of Fluralaner in cats · Medicines most reported with loss of appetite