Behaviour change after Fluralaner (Bravecto) in cats

535 reports to the FDA describe behaviour change in cats given Fluralaner. That is 5.0% of all reports for this medicine, compared with 5.4% across reports for all cat medicines.

535Reports
62%Marked serious
29%Recovered
5.2%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
257 60%
1–2 days
80 19%
3–7 days
33 7.7%
1–4 weeks
24 5.6%
Over a month
32 7.5%

How the animals did

Recovered
149 28%
Recovered with lasting effects
8 1.5%
Still unwell when reported
295 55%
Died
14 2.6%
Euthanised
14 2.6%
Not known
55 10%

Problems reported at the same time

Age of the animals

Under 1 year
30
1–3 years
159
4–7 years
135
8–11 years
99
12+ years
82

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause behaviour change in cats?
535 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Behaviour change with similar medicines

All reported side effects of Fluralaner in cats · Medicines most reported with behaviour change