Kidney problems after Fluralaner (Bravecto) in cats

156 reports to the FDA describe kidney problems in cats given Fluralaner. That is 1.5% of all reports for this medicine, compared with 4.5% across reports for all cat medicines, so it is reported less often than average with this medicine.

156Reports
97%Marked serious
10%Recovered
32%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
38 29%
1–2 days
42 33%
3–7 days
15 12%
1–4 weeks
13 10%
Over a month
21 16%

How the animals did

Recovered
6 3.8%
Recovered with lasting effects
10 6.4%
Still unwell when reported
66 42%
Died
17 11%
Euthanised
33 21%
Not known
24 15%

Problems reported at the same time

Age of the animals

Under 1 year
5
1–3 years
25
4–7 years
25
8–11 years
35
12+ years
61

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause kidney problems in cats?
156 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

All reported side effects of Fluralaner in cats · Medicines most reported with kidney problems