Diphenhydramine side effects in cats

368 reports sent to the FDA between 1999 and 2026 involve Diphenhydramine in cats. The most reported problems were vomiting, loss of appetite, lethargy. 67% were marked serious, and where it was recorded, signs eased after stopping the medicine in 0% of cases.

368Reports
67%Marked serious
1.4%Only medicine involved
29%Recovered
23%Died or euthanised
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About this medicine

Type: medicine.

Most reported side effects

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a cat still getting fleas or heartworm), not about a side effect.

Didn't stop fleas
5 1.4%

How soon problems started

Same day
198 59%
1–2 days
64 19%
3–7 days
22 6.6%
1–4 weeks
29 8.7%
Over a month
22 6.6%

Time from the first dose to the first sign, where both dates were reported (335 reports).

How the animals did

Recovered
106 29%
Still unwell when reported
120 33%
Died
45 12%
Euthanised
40 11%
Not known
57 15%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other medicines for cats