Itching after Diphenhydramine in cats

34 reports to the FDA describe itching in cats given Diphenhydramine. That is 9.2% of all reports for this medicine, compared with 8.9% across reports for all cat medicines.

34Reports
62%Marked serious
21%Recovered
5.9%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
15 48%
1–2 days
8 26%
3–7 days
3 9.7%
1–4 weeks
3 9.7%
Over a month
2 6.5%

How the animals did

Recovered
7 21%
Still unwell when reported
16 47%
Euthanised
2 5.9%
Not known
9 26%

Problems reported at the same time

14 41%
Application site reaction
9 26%
Skin rash or irritation
5 15%

Age of the animals

Under 1 year
4
1–3 years
13
4–7 years
5
8–11 years
6
12+ years
6

About this medicine

Type: medicine.

Questions owners ask

Can Diphenhydramine cause itching in cats?
34 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Itching with similar medicines

All reported side effects of Diphenhydramine in cats · Medicines most reported with itching