Ketonuria after Bexagliflozin (Bexacat) in cats

130 reports to the FDA describe ketonuria in cats given Bexagliflozin. That is 3.2% of all reports for this medicine, compared with 0.5% across reports for all cat medicines, so it is reported unusually often with this medicine.

130Reports

72%Marked serious

6.9%Recovered

26%Died or euthanised

4 daysTypical onset

How soon it started

Same day

18 16%

1–2 days

18 16%

3–7 days

40 34%

1–4 weeks

13 11%

Over a month

27 23%

How the animals did

Recovered

9 6.9%

Still unwell when reported

55 42%

Died

5 3.8%

Euthanised

29 22%

Not known

32 25%

Problems reported at the same time

73 56%

53 41%

51 39%

49 38%

Diabetic ketoacidosis

47 36%

Liver problems

47 36%

Hyperglycaemia

41 32%

Weight loss

40 31%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Bexagliflozin treats diabetes in cats (oral, an SGLT2 inhibitor).

Products with this ingredient include Bexacat. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bexagliflozin cause ketonuria in cats?: 130 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Ketonuria with similar medicines

Ketonuria after Velagliflozin (Senvelgo) 574 reports · 12% of its reports
Ketonuria after Insulin 31 reports · 0.8% of its reports

All reported side effects of Bexagliflozin in cats · Medicines most reported with ketonuria