Liver problems after Bexagliflozin (Bexacat) in cats

The FDA has received 309 reports of liver problems in cats after Bexagliflozin. That is 7.6% of all reports for this medicine, compared with 2.8% across reports for all cat medicines, so it is reported unusually often with this medicine.

309Reports
58%Marked serious
4.5%Recovered
24%Died or euthanised
13 daysTypical onset
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How soon it started

Same day
19 7.4%
1–2 days
29 11%
3–7 days
59 23%
1–4 weeks
55 21%
Over a month
95 37%

How the animals did

Recovered
14 4.5%
Still unwell when reported
145 47%
Died
15 4.9%
Euthanised
60 19%
Not known
75 24%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
5
4–7 years
64
8–11 years
136
12+ years
92

About this medicine

Bexagliflozin treats diabetes in cats (oral, an SGLT2 inhibitor).

Products with this ingredient include Bexacat. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bexagliflozin cause liver problems in cats?
309 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 13 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Bexagliflozin in cats · Medicines most reported with liver problems