Liver problems after Insulin in cats

The FDA has received 155 reports of liver problems in cats after Insulin. That is 4.1% of all reports for this medicine, compared with 2.8% across reports for all cat medicines.

155Reports

72%Marked serious

6.5%Recovered

34%Died or euthanised

3 daysTypical onset

How soon it started

Same day

19 21%

1–2 days

24 27%

3–7 days

17 19%

1–4 weeks

9 10%

Over a month

21 23%

How the animals did

Recovered

8 5.2%

Recovered with lasting effects

2 1.3%

Still unwell when reported

47 30%

Died

21 14%

Euthanised

32 21%

Not known

45 29%

Problems reported at the same time

Loss of appetite

77 50%

Lethargy

57 37%

Death

54 35%

Didn't work as expected

53 34%

45 29%

45 29%

39 25%

38 25%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Insulin treats diabetes.

Questions owners ask

Can Insulin cause liver problems in cats?: 155 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

Liver problems after Velagliflozin (Senvelgo) 339 reports · 7.1% of its reports
Liver problems after Bexagliflozin (Bexacat) 309 reports · 7.6% of its reports
Liver problems after Methimazole 148 reports · 8.3% of its reports

All reported side effects of Insulin in cats · Medicines most reported with liver problems