Ketonuria after Insulin in cats

The FDA has received 31 reports of ketonuria in cats after Insulin. That is 0.8% of all reports for this medicine, compared with 0.5% across reports for all cat medicines, so it is reported unusually often with this medicine.

31Reports

84%Marked serious

3.2%Recovered

26%Died or euthanised

4 daysTypical onset

How soon it started

Same day

3 12%

1–2 days

4 16%

3–7 days

10 40%

1–4 weeks

5 20%

Over a month

3 12%

How the animals did

Recovered

1 3.2%

Still unwell when reported

15 48%

Died

2 6.5%

Euthanised

6 19%

Not known

7 23%

Problems reported at the same time

23 74%

15 48%

14 45%

13 42%

12 39%

12 39%

12 39%

11 35%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Insulin treats diabetes.

Questions owners ask

Can Insulin cause ketonuria in cats?: 31 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Ketonuria with similar medicines

Ketonuria after Velagliflozin (Senvelgo) 574 reports · 12% of its reports
Ketonuria after Bexagliflozin (Bexacat) 130 reports · 3.2% of its reports

All reported side effects of Insulin in cats · Medicines most reported with ketonuria