Kidney problems after Omeprazole in horses

21 reports to the FDA describe kidney problems in horses given Omeprazole. That is 1.1% of all reports for this medicine, compared with 1.6% across reports for all horse medicines, so it is reported less often than average with this medicine.

21Reports

76%Marked serious

19%Recovered

24%Died or euthanised

4 daysTypical onset

How soon it started

Same day

2 11%

1–2 days

6 32%

3–7 days

6 32%

1–4 weeks

3 16%

Over a month

2 11%

How the animals did

Recovered

3 14%

Recovered with lasting effects

1 4.8%

Still unwell when reported

5 24%

Died

1 4.8%

Euthanised

4 19%

Not known

7 33%

Problems reported at the same time

Loss of appetite

12 57%

Lethargy

9 43%

Neutrophilia

7 33%

6 29%

6 29%

6 29%

5 24%

Didn't work as expected

5 24%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Omeprazole cause kidney problems in horses?: 21 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

Kidney problems after Ceftiofur 23 reports · 1.9% of its reports
Kidney problems after Flunixin Meglumine 47 reports · 7.6% of its reports
Kidney problems after Clodronate Disodium 95 reports · 31% of its reports

All reported side effects of Omeprazole in horses · Medicines most reported with kidney problems