Colic after Moxidectin (ProHeart 6) in horses
The FDA has received 26 reports of colic in horses after Moxidectin. That is 1.9% of all reports for this medicine, compared with 4.2% across reports for all horse medicines, so it is reported less often than average with this medicine.
26Reports
65%Marked serious
62%Recovered
15%Died or euthanised
Same dayTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Moxidectin prevents heartworm disease (monthly topical, or a 6- or 12-month injection for dogs).
Products with this ingredient include ProHeart 6, ProHeart 12. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.
Questions owners ask
- Can Moxidectin cause colic in horses?
- 26 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within the same day of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Colic with similar medicines
- Colic after Ivermectin + Praziquantel 71 reports · 2.7% of its reports
- Colic after Moxidectin + Praziquantel 58 reports · 16% of its reports
All reported side effects of Moxidectin in horses · Medicines most reported with colic