Tachycardia after Ivermectin + Praziquantel in horses
The FDA has received 29 reports of tachycardia in horses after Ivermectin + Praziquantel. That is 1.1% of all reports for this medicine, compared with 2.0% across reports for all horse medicines, so it is reported less often than average with this medicine.
29Reports
17%Marked serious
14%Recovered
21%Died or euthanised
–Typical onset
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How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Ivermectin prevents heartworm disease (monthly). Praziquantel treats tapeworms.
Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.
Questions owners ask
- Can Ivermectin + Praziquantel cause tachycardia in horses?
- 29 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Tachycardia with similar medicines
- Tachycardia after Moxidectin (ProHeart 6) 24 reports · 1.8% of its reports
All reported side effects of Ivermectin + Praziquantel in horses · Medicines most reported with tachycardia