Urinary tract infection after Ursodiol in dogs

The FDA has received 35 reports of urinary tract infection in dogs after Ursodiol. That is 4.8% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

35Reports
77%Marked serious
11%Recovered
14%Died or euthanised
72 daysTypical onset
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How soon it started

Same day
3 12%
1–2 days
0 0.0%
3–7 days
1 3.8%
1–4 weeks
7 27%
Over a month
15 58%

How the animals did

Recovered
4 11%
Still unwell when reported
16 46%
Euthanised
5 14%
Not known
10 29%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
1
4–7 years
0
8–11 years
20
12+ years
14

About this medicine

Type: medicine.

Questions owners ask

Can Ursodiol cause urinary tract infection in dogs?
35 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 72 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Urinary tract infection with similar medicines

All reported side effects of Ursodiol in dogs · Medicines most reported with urinary tract infection